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Master thesis: Get the odor: CAR enzymes for aliphatic acid modification

FEMtech stipend


Mehr Jobs von ACIB - Austrian Centre of Industrial Biotechnology
Kontakt: Dr. Margit Winkler
Email: Nicht verfügbar
Telefon: 0316-873 9333

ACIB - the Austrian Centre of Industrial Biotechnology - is one of the leading research centers in the field of industrial biotechnology. ACIB is dedicated to joint research at the industrial-academic interface. Seven Austrian Universities and more than 25 leading industry partners are working together within the ACIB research program. In Graz we currently offer a

 

Master thesis

Get the odor: CAR enzymes for aliphatic acid modification

 

More than probably any other sense, smell evokes memories and aldehydes are the key ingredients for creating these moments. Bioreduction of carboxylic acids to aldehydes by Carboxylic Acid Reductases (CARs) show promising results for a more sustainable route to aldehydes.

 

Your focus:         

  • heterologous expression of CARs in E. coli and/or Pichia pastoris
  • investigation of the substrate scope in vivo and in vitro
  • enzyme purification and characterization

 

The ideal master candidate studies molecular biology, biochemistry or biotechnology, has very good theoretical and practical knowledge of:

  • molecular biology methods (PCR, DNA extraction and purification, cloning);
  • bioinformatic tools (SnapGene, PyMOL)
  • microbiological work (cultivation, cell disruption, protein purification, SDS-PAGE)
  • analytical methods (HPLC and GC analysis for activity analysis)

 

However, knowledge of all techniques is not mandatory. Applicants should be enthusiastic to reach defined goals, be motivated to learn new techniques and present their results. This master thesis will be compensated by a FEMtech stipend to promote female students in technical fields and life science.  

Please submit the application comprising a cover letter and a detailed CV via our application portal: application.acib.at (ref. 06_2019)

Deadline for applications: September 20th 2019

Starting date: October 2019

Payment (FEMtech stipend for 6 months, full-time): 1400 €/month

If you would like further information, please contact Dr. Margit Winkler (margit.winkler@acib.at) or come by at Petersgasse 14, 2nd floor, 8010 Graz.

 

Please find the complete offer at: https://filemaker.acib.at/fmi/webd/mailbox?homeurl=about:blank&script=execapp


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